1. In the F^+, the two strands of the double helix of the Fertility (F) factor (a plasmid) separate. 2. One of the two strands moves into the recipient (F^-) cell. 3. The other strand remains in the donor cell. 4. Both strands are replicated, with clockwise rotation of the circles. 5. Both the donor and the recipient cells are now F^+ after conjugation.