Denatured,   single-stranded   DNA   fragments  can  reassociate  into
   complementary  double  strands.  The single-stranded DNA concentration
   (C) can be plotted against a logarithmic scale of the product of C[0]t
   (initial concentration of DNA single strands), and t (time).

   The  half-reaction  time  C[0]t[1/2]  increases  as  the fragment size
   increases,  so  this  can be used to estimate genome sizes. Repetitive
   DNA  sequences  in some eukaryotic DNA allow them to have much shorter
   C[0]t[1/2].