A tumor-inducing (Ti) plasmid of the bacterium Agrobacterium tumifaciens can be used as a vector for DNA cloning in plants.

The plasmid T DNA, necessary for integration, are combined with bacterial DNA that contain an origin of replication (ori), restriction sites and antibiotic resistance genes (KanR and tetR).

When the bacterium infects a plant, the T DNA, together with any cloned DNA, integrates into a host chromosome, producing a transgenic plant.

This process is caled transformation.