DNA: secret of photo 51 (Nap=572.8092 FRA, Aur VHS=VCT 572.86 NOV)
Z-DNA
is left-handed
restore
10.4 nucleotides per turn.
in situ
= in place, undisturbed
Molymod/Tinkertoy DNA
Paper chromatography of coffee?
1=A 2=B 3=R 4=B 5=D
6=D 7=C 8=D 9=D 10=B
11=C 12=A 13=A 14=A 15=B
16=D 17=E 18=A 19=E 20=B
1=... did not 2=DNase 3=Reverse
4=T 5=5-methyl uracil???
6=Rosalind 7=... 30% 8=antiparallel
9=5'–3'? 10=TCATGCGATC
11=FISH 12=Shorter 13=RNase?
14=Protein 15=C-3' and C-5'!!!
16=...inside of the 17=slowly 18=longer
19=The retrovirus 20=T
21=... directions 22=5' CAGTCAAGCAT 3
See chap 9 CD
- Martha Chase: lab assistant for Hershey, 1952 paper. USC PhD 1964.
- Sulfur-containing amino acids: CYS, MET
- Isotope: diff atomic mass neutrons; unstable, decay:
emit weak alpha (He-4), beta (electron), high energy gamma radiation:
Geiger detects alpha & beta; scintillation for gamma; P32 & S35 is beta
- Transfection: infection by only the viral nucleic acid
- Interferon: proteins of immune system - replication of viruses
- Esters formed in condensation reaction between alcohol and acid
- Tubercle Bacillus: Tuberculosis
- Angstrom = 0.1 nm
- Rosalind Franklin 100 hours exposure, died 1958 age 37 ovarian cancer
Marie Curie age 66 aplastic anemia, Nobel Physics & Chemistry
- Z-DNA is left-handed
- Ultracentrifuge 100k rpm