Gene B | Gene A | |||
---|---|---|---|---|
Precursor | ↓ | Black | ↓ | Agouti |
Molecule | → | Pigment | → | Pattern |
(colorless) | B - | A - |
In the presence of a B allele,
black
pigment can be made from a colorless substance. In the presence of an A allele,
the black
pigment is deposited during the development of hair
in a pattern producing the agouti
phenotype.
If the aa genotype occurs, all of the hair remains black
.
If the bb genotype occurs,
no black
pigment is produced,
regardless of the presence of the A or a alleles,
and the mouse is albino
.
Therefore, the homonzygous b genotype masks or suppresses the expression of the A allele;
this is referred to as recessive epistasis.