Methods of Determining Allele Frequencies from Data on Genotypes
A survey of 100 French individuals from Brittany gave these genotypes.
Allele frequencies can be calculated by
- Counting Alleles: just add the alleles.
For example, frequency of the CCR5l (1) allele is (158+20)/200 = 178/200 = 0.89.
- From Genotype Frequencies: add the homozygotes and half the heterozygotes.
For example, frequency of the CCR5l (1) allele is 0.79 + (0.5)0.20 = 0.89.