For a population in Hardy-Weinberg equilibrium,
genotype frequencies can be calculated from allele frequencies
using Mendelian principles of segregation and simple probability.
Here the frequency of the A allele is 0.7, and the frequency of the a allele is 0.3.
The genotype frequencies in the next generation are:
- AA: 0.49
- aa: 0.09
- Aa: 0.21 x 2 = 0.42
Under Hardy-Weinberg equilibrium, allele frequencies in the next generation should remain
constant.
For example, the A allele should be 0.49 + (0.5 x 0.42) = 0.7.