Chapter 11: DNA Replication and Recombination

PHONE CORD: supercoiling? demo
ZIPPER fannypack: leading strand demo
Meselson-Stahl density gradient (sedimentation equilibrium)
delta, xi, psi; holo=whole? Taylor-Woods-Hughes
telomere Tetrahymena (ciliate) TTGGGG, vertebrates TTAGGG.
Recombination results in altered arrangement of alleles.
gene_conversion: See ebook
1=	2=	3=	4=	5=
6=	7=	8=	9=	10=
11=	12=	13=	14=	15=
16=	17=	18=	19=	20=







1=Conservative		2=III			3=ATP
4=Gyrase		5=3'-OH

6=lagging 		7=RNA ligase		8=3' to 5' exonuclease
9=... fork		10=Found

11=Homologous		12=Gene conversion?	13=discontinuous
14=Discontinuous	15=ligase

16=I			17=... eukaryotes	18=F
19=conversion		20=F

21=polymerase		22=homologous 		23=T
  1. Okazaki died of leukemia a few years after his discovery: exposed to radiation in Hiroshima
  2. DNA polymerase epsilon
  3. Platanus Sycamore twig: lenticels?