Chapter 22: Applications and Ethics of Biotechnology

DNA_microarray DNA from blood sample.
VNTR Satellite DNA is highly repetitive; VNTRs are minisatellite: middle repetitive
gene_therapy adenosine deaminase removes amino group; ADA/ADA2 ratio required to kill parasites. ADA2 may lead to autism.
recombinant_insulin Pancreas synthesize preproinsulin; add sugars and phosphate groups to fold correctly.
Eli Lilly 80's Humulin; now analogs Humalog, Novolog (fast)
sickle-cell_anemia the restriction enzime is Mst TWO. The GAG normal DNA is on non-coding strand, complementary to CTC
STR These tiny repeats are analyzed by PCR, not RFLP.
ASOs can ID alleles to single nucleotide, RFLP depends on restriction site mutation; normal ASO GAG binds to CTC.
transgenic_crops Canola=Canadian oil, low acid, from rapeseed (high acid). Low sat fat, but ω-3 replaced w/ trans fats? Biodiesel?
nuclear_injection Emphysema pulmonary disease: chemicals, tobacco smoke
transfection = infection by transformation in animal cells.
QH442.2 .C743 2002: Creation#23:30 woman egg donor, Judson's skin cells thru zona pellucida (glycoprotein) - 32:30
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